Collatamp G is used for local haemostasis of capillary, parenchymatous and seeping haemorrhages in areas with a high risk of infection (determined by the surgeon on a case-by-case basis, including patient-related, surgery-related, and physiological factors). After implantation of Collatamp G, systemic gentamicin plasma amounts may temporarily reach therapeutic levels. Collatamp G is a resorbable gentamicin collagen implant which may be used in different surgical specialties.
References:
1. Almeida, C.E.P.C., Reis, L., Carvalho, L. and Almeida, C.M.C., 2014. Collagen implant with gentamicin sulphate reduces surgical site infection in vascular surgery: a prospective cohort study. International Journal of Surgery, 12(10), pp.1100-1104.
2. Kaczmarek, K., Strzelecki, A., Ptaszyński, P., Wranicz, J.K. and Cygankiewicz, I., 2021. The safety, efficacy, and cost-effectiveness of gentamycin-collagen sponge in multicomponent prevention strategy of cardiac implantable electronic device infections—a single-center experience. Kardiologia Polska (Polish Heart Journal), 79(10), pp.1079-1085.
3. Monaco, C., Barone, L., Cammalleri, V., Stifano, G., Magliano, G., Geuna, F., Romeo, F. and Sergi, D., 2022. Local gentamicin-collagen sponge reduces cardiovascular implantable electronic device infections and pocket hematoma. European review for medical and pharmacological sciences, 26(14), pp.5218-5224.
4. Friberg, Ö., Svedjeholm, R., Söderquist, B., Granfeldt, H., Vikerfors, T. and Källman, J., 2005. Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 79(1), pp.153-161.
5. Friberg, Ö., Dahlin, L.G., Källman, J., Kihlström, E., Söderquist, B. and Svedjeholm, R., 2009. Collagen-gentamicin implant for prevention of sternal wound infection; long-term follow-up of effectiveness. Interactive cardiovascular and thoracic surgery, 9(3), pp.454-458.
6. Benedetto, U., Raja, S.G. and Harefield Cardiac Outcomes Research Group, 2014. Scoring system to guide decision making for the use of gentamicin-impregnated collagen sponge to prevent deep sternal wound infection. The Journal of Thoracic and Cardiovascular Surgery, 148(5), pp.2390-2396.
7. Kowalewski, M., Pawliszak, W., Zaborowska, K., Navarese, E.P., Szwed, K.A., Kowalkowska, M.E., Kowalewski, J., Borkowska, A. and Anisimowicz, L., 2015. Gentamicin-collagen sponge reduces the risk of sternal wound infections after heart surgery: meta-analysis. The Journal of Thoracic and Cardiovascular Surgery, 149(6), pp.1631-1640.
8. National Institute for Health and Care Excellence, 2019. Surgical site infections: prevention and treatment. NICE guideline [NG125] Evidence reviews. Available at: https://www.nice.org.uk/guidance/ng125/evidence/evidence-reviews-april-2019-6727104397?tab=evidence [Accessed February 2023].
9. Han, J.S., Kim, S.H., Jin, S.W., Lee, S.H., Kim, B.J., Kim, S.D. and Lim, D.J., 2016. The use of gentamicin-impregnated collagen sponge for reducing surgical site infection after spine surgery. Korean Journal of Spine, 13(3), p.129.
10. Varga, M., Sixta, B., Bem, R., Matia, I., Jirkovska, A. and Adamec, M., 2014. Application of gentamicin-collagen sponge shortened wound healing time after minor amputations in diabetic patients–a prospective, randomised trial. Archives of Medical Science, 10(2), pp.283-287.
11. Rutkowski, A., Pietrzak, L., Kryński, J., Zając, L., Bednarczyk, M., Olesiński, T., Szpakowski, M., Saramak, P., Pierzankowski, I., Hevelke, P. and Surowski, P., 2018. The gentamicin-collagen implant and the risk of distant metastases of rectal cancer following short-course radiotherapy and curative resection: the long-term outcomes of a randomized study. International journal of colorectal disease, 33(8), pp.1087-1096.
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