Overview
Prevention of Infection
- Gentamicin is an antibiotic from aminoglycosides class.1
- Gentamicin exhibits bactericidal activity against a broad spectrum of micro-organisms.2
- This product contains gentamicin sulfate at a locally effective dose.3
Local concentration of gentamicin
in soft tissue2
in soft tissue2
After implantation of Collatamp®G, systemic gentamicin plasma amounts may temporarily reach therapeutic levels.3
Low and short-lasting systemic exposure reported below toxicity thresholds2
Prolonged use may lead to the emergence of resistant organisms. There is noevidence that single use Collatamp®G administration in patients promotes or induces the formation of resistance against gentamicin.3
*MIC: Minimal Inhibitory Concentration.
**Sulmycin® Implant E: Tradename of the registered medicinal product in Germany with collagen and gentamicin sulfate equivalent to Collatamp®G, the only difference is the origin of the collagen (equine and not bovine).
**Sulmycin® Implant E: Tradename of the registered medicinal product in Germany with collagen and gentamicin sulfate equivalent to Collatamp®G, the only difference is the origin of the collagen (equine and not bovine).
References:
- Maczynska B. et al., Journal Plos One. 2019 (June):1-14.
- Ruszczak Z, Friess W. Collagen as a carrier for on-site delivery of antibacterial drugs. Adv Drug Deliv Rev. 2003;55:1679-98.
- Instructions For Use, Collatamp®G.